产品详情 |
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Antigenic Specificity | CD87 (UPAR) |
Clone | VIM5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | PerCP-eFluor 710 conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD87 (UPAR) Monoclonal Antibody (VIM5), PerCP-eFluor 710, eBioscience™. Urokinase plasminogen activator receptor (uPAR), also known as CD87, is a glycolipid anchored cell surface protein consisting of three homologous domains. It binds uPA with high affinity and enhances and localizes uPA catalyzed plasminogen activation, and thereby plays a key role in cancer invasion and in several tissue remodelling processes. In addition uPAR also binds to vitronectin and may thereby have biological functions independent of its role in uPA mediated proteolysis. Elevated levels of uPAR are associated with poor prognosis in many types of cancer. |
Immunogen | n/a |
Other Names | PLAUR, U-PAR, UPAR, URKR, monocyte activation antigen Mo3, u-plasminogen activator receptor form 2, urokinase plasminogen activator surface receptor |
Gene, Accession # | Entrez: 5329; Uniprot: Q03405 |
Catalog # | 46-3879-42 |
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Order / More Info | CD87 (UPAR) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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