| 产品详情 |
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| Antigenic Specificity | Nephrin |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Nephrin Polyclonal Antibody. Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease. Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss. Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2. Nephrin, a recently identified protein is a member of a group of podocyte proteins that constitute major component of the slit diaphragm especially in the foot process. Nephrin, a cell adhesion molecule, may play a crucial role in maintaining the glomerular filtration barrier. Recent studies have suggested that mutations in the gene for Nephrin reportedly lead to congenital nephrosis. Three n |
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| Immunogen | n/a |
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| Other Names | Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN |
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| Gene, Accession # | Entrez: 4868, 54631, 64563; Uniprot: O60500, Q9QZS7, Q9R044 |
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| Catalog # | PA5-79756 |
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| Price | |
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| Order / More Info | Nephrin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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