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Antigenic Specificity | Spectrin beta-1 |
Clone | 4C3 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 0.5-2 µg/test, Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Spectrin beta-1 Monoclonal Antibody (4C3). Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps these cells maintain their characteristic biconcave shape while remaining flexible and elastic. Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit which associate in a side-to-side, antiparallel configuration to form a 100 nm rod-like structure. Sp in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin. A newly introduced nomenclature designates the Sp subunits of the erythrocyte as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms of each are designated as epsilon- |
Immunogen | n/a |
Other Names | Sp, SPTB1 |
Gene, Accession # | Entrez: 20741, 314251, 6710; Uniprot: P11277, P15508 |
Catalog # | MA3-062 |
Price | |
Order / More Info | Spectrin beta-1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 9142435 |
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