产品详情 |
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Antigenic Specificity | Spectrin beta-4 |
Clone | S393-2 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: Assay-Dependent, Immunofluorescence: 1:100, Immunohistochemistry (PFA fixed): 1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Spectrin beta-4 Monoclonal Antibody (S393-2). Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart. Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier. |
Immunogen | n/a |
Other Names | BetaIV-spectrin sigma1, Non-erythrocytic spectrin beta chain 4, Non-erythroidspectrin beta chain 3, SPTBN4, SPTBN3, Spnb4, KIAA1642, EMBL BAB83243.1, Ensembl ENSRNOP00000028393 |
Gene, Accession # | Entrez: 308458, 57731, 80297; Uniprot: Q9H254 |
Catalog # | MA5-27608 |
Price | |
Order / More Info | Spectrin beta-4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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