| 产品详情 |
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| Antigenic Specificity | SPEN |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SPEN Polyclonal Antibody. May serve as a nuclear matrix platform that organizes and integrates transcriptional responses. In osteoblasts, supports transcription activation: synergizes with RUNX2 to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE). Has also been shown to be an essential corepressor protein, which probably regulates different key pathways such as the Notch pathway. Negative regulator of the Notch pathway via its interaction with RBPSUH, which prevents the association between NOTCH1 and RBPSUH, and therefore suppresses the transactivation activity of Notch signaling. Blocks the differentiation of precursor B-cells into marginal zone B-cells. Probably represses transcription via the recruitmen |
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| Immunogen | n/a |
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| Other Names | KIAA0929; MINT; SHARP |
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| Gene, Accession # | Entrez: 23013; Uniprot: Q96T58 |
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| Catalog # | PA5-65605 |
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| Price | |
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| Order / More Info | SPEN Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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