| 产品详情 |
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| Antigenic Specificity | ErbB3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ErbB3 Polyclonal Antibody. ErbB3, a member of the EGF receptor family, binds and is activated by neuregulins and NTAK. It potentially forms a heterodimer with each of the other ERBB receptors. This protein is predominantly expressed in epithelial tissues and brain. The cytoplasmic part of the receptor may interact with the SH2 or SH3 domains of many signal-transducing proteins. Ligand-binding may increase phosphorylation on tyrosine residues and promote its association with the p85 subunit of phosphatidylinositol 3-kinase ErbB3 is overexpressed in a subset of human mammary tumors. |
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| Immunogen | n/a |
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| Other Names | Tyrosine kinase-type cell surface receptor HER3; ERBB3 |
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| Gene, Accession # | Entrez: 13867, 2065; Uniprot: P21860, Q61526 |
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| Catalog # | PA5-14636 |
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| Price | |
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| Order / More Info | ErbB3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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