产品详情 |
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Antigenic Specificity | ErbB4 |
Clone | H4.72.8 (Ab72) |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | biotin conjugate |
Size | 500 µL |
Concentration | n/a |
Applications | Flow Cytometry: Assay Dependent, Western Blot: 1:50-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ErbB4 Monoclonal Antibody (H4.72.8 (Ab72)), Biotin. ErbB 4 (Her-4, c-erbB-4, v-erbB-4) is a member of the class I receptor kinase family. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases). ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself. Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism |
Immunogen | n/a |
Other Names | avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, proto-oncogene-like protein c-ErbB-4, receptor tyrosine-protein kinase erbB-4, tyrosine kinase-type cell surface receptor HER4 |
Gene, Accession # | Entrez: 2066; Uniprot: Q15303 |
Catalog # | MA5-13013 |
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Order / More Info | ErbB4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10706134, 12473609, 14576062, 15197768, 16398612, 16407398, 16463386, 17392498, 17562386, 18395045, 19103753, 20847549, 21060844, 21115466, 22415601, 23035098, 23432624 |
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