| 产品详情 |
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| Antigenic Specificity | ErbB4 |
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| Clone | H4.77.16 (Ab77) |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunoprecipitation: 2 µg/mg protein lysate, Western Blot: 1:50-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ErbB4 Monoclonal Antibody (H4.77.16 (Ab77)). ErbB 4 (Her-4, c-erbB-4, v-erbB-4) is a member of the class I receptor kinase family. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases). ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself. Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, trans |
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| Immunogen | n/a |
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| Other Names | avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, proto-oncogene-like protein c-ErbB-4, receptor tyrosine-protein kinase erbB-4, tyrosine kinase-type cell surface receptor HER4 |
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| Gene, Accession # | Entrez: 13869, 2066, 59323; Uniprot: Q15303, Q61527, Q62956 |
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| Catalog # | MA5-12888 |
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| Price | |
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| Order / More Info | ErbB4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10638965, 10781891, 11212228, 15561777, 15979989, 16398612, 17562386, 23432624, 26891847 |
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