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Antigenic Specificity | ErbB4 |
Clone | HFR1 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b |
Format | purified |
Size | 200 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.5-2 µg / test, Immunocytochemistry: 1:50, Immunofluorescence: 1:50, Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: Assay dependent, Western Blot: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ErbB4 Monoclonal Antibody (HFR1). ErbB 4 (Her-4, c-erbB-4, v-erbB-4) is a member of the class I receptor kinase family. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases). ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself. Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, c |
Immunogen | n/a |
Other Names | C-erbB-4, Avian erythroblastic leukemia viral (verbb2) oncogene homolog 4, ERBB4, p180erbB4, Tyrosine kinase type cell surface receptor HER4, Verb a e |
Gene, Accession # | Entrez: 13869, 2066; Uniprot: Q15303, Q61527 |
Catalog # | MA1-861 |
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Order / More Info | ErbB4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 11297265, 11825873, 12800145, 15325672, 15480434, 15713896, 15770691, 15818618, 15980985, 16007579, 16027731, 16100239, 16157365, 16330088, 16397033, 16429394, 16507107, 16962163, 17251007, 17486069, 17987795, 18006009, 18426733, 18676864, 19304440, 20331873, 21092257, 23313737, 24256036, 24744091, 27377368 |
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