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| Product Name | Carbonic Anhydrase IX/XII Inhibitor (CAIX Inhibitor) |
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| Description | Purity ~98% (HPLC). A cell permeable benzenesulfonamide Carbonic Anhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (Ki = 0.9nM and 5.7nM, respectively) against two other physiologically relevant hCA isoforms (Ki = 23.4nM and 15nM for hCA I and hCA II, respectively), as compared with another CA inhibitor AAZ (Ki = 250nM, 12nM, 25nM, and 5.7nM for hCA I, hCA II, hCA IX, and hCA XII, respectively). It is shown to effectively inhibit the formation of metastases by 4T1 breast cancer cells in a mouse model dose-dependently at pharmacologic concentrations of 15-45mg/kg. Formula: C13H12N4O5S Molecular Weight: 336.3 Solubility: DMSO (50mg/ml) |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217247 |
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| Order / More Info | Carbonic Anhydrase IX/XII Inhibitor (CAIX Inhibitor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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