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Antigenic Specificity | Glucocorticoid Receptor |
Clone | 6E6 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1/200 - 1/400, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glucocorticoid Receptor Monoclonal Antibody (6E6). The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Tissue specificity: Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart |
Immunogen | n/a |
Other Names | GCCR, GCR, GR, GRL, glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; nuclear receptor subfamily 3 group C member 1 variant DL-1; nuclear receptor subfamily 3 group C member 1 variant NS-1 |
Gene, Accession # | Entrez: 14815, 2908; Uniprot: P04150, P06537 |
Catalog # | MA5-15801 |
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Order / More Info | Glucocorticoid Receptor Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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