| 产品详情 |
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| Product Name | Celastrol |
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| Description | Purity >98% by TLC. Cell-permeable. An Antioxidant, anti-inflammatory and immunosuppressive agent. Suppresses LPS-induced cytokine release in macrophages and monocytes (IC50 = 40 nM for IL-1Beta and IL-1a, 80 nM for IL-6, 110 nM for prostaglandin E2 and 210 nM for IL-8 and TNF-a). Suppresses nitric oxide (NO) production (IC50 = 230 nM) and LPS-induced NF- Kappa B activation (IC50 = 270 nM). Inhibits chymotrypsin-like activity of 20S proteasome (IC50 = 2.5 µM) and lipid peroxidation induced by ADP and Fe2+ in rat liver mitochondria (IC50 = 7 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (9-Beta,13A,14-Beta,20A)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid |
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| Gene, Accession, CAS # | CAS: 34157-83-0 |
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| Catalog # | LS-H2606 |
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| Price | |
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| Order / More Info | Celastrol from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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