| 产品详情 |
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| Product Name | Celastrol |
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| Description | Purity >98% by HPLC. A triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). Displays an IC50 value of 7 µM (isolated rat liver assay of lipid peroxidation), equivalent to about 15 times the antioxidant potency of a-Tocopherol. Also inhibits topoisomerase II activity in vitro (IC50 = 7.41 µM). A potent proteasome inhibitor, that suppresses human prostate cancer growth in nude mice. It potentiates TNF-induced apoptosis and suppresses invasion of tumour cells by inhibiting NF-?B-regulated gene products and TAK1-mediated NF-?B activation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2R,4aS,6aS,6aR,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid |
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| Gene, Accession, CAS # | CAS: 34157-83-0 |
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| Catalog # | LS-H11252 |
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| Price | |
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| Order / More Info | Celastrol from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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