| 产品详情 |
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| Antigenic Specificity | TCTN3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 4 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 4 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TCTN3 Polyclonal Antibody. TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the |
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| Immunogen | n/a |
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| Other Names | RP11-7D5.3, C10orf61, TECT3; tectonic 3; tectonic-3 |
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| Gene, Accession # | Entrez: 26123, 309486, 67590; Uniprot: Q6NUS6, Q8R2Q6 |
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| Catalog # | PA5-20985 |
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| Price | |
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| Order / More Info | TCTN3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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