| 产品详情 |
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| Antigenic Specificity | TMC6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TMC6 Polyclonal Antibody. Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes, EVER1 and EVER2, located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family. EVER1 possesses eight trans-membrane domains and two leucine zipper motifs. EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1 |
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| Immunogen | n/a |
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| Other Names | EV1, EVER1, EVIN1, LAK-4P; epidermodysplasia verruciformis 1; epidermodysplasia verruciformis protein 1; expressed in activated T/LAK lymphocytes; protein LAK-4; transmembrane channel-like protein 6 |
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| Gene, Accession # | Entrez: 11322, 217353; Uniprot: Q7TN60, Q7Z403 |
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| Catalog # | PA5-20505 |
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| Price | |
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| Order / More Info | TMC6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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