| 产品详情 |
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| Antigenic Specificity | TMC6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 µl |
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| Concentration | lyophilized |
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| Applications | Western Blot: 1:800 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TMC6 Polyclonal Antibody. TMC6 interacts with, and forms a complex with the zinc transporter 1, SLC30A1, and localizes to the endoplasmic reticulum, nuclear membrane and Golgi apparatus. The inactivation of the TMC6 gene has been implicated in the skin disorder epidermodysplasia verruciformis (EV), an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. TMC6 encodes integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel |
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| Immunogen | n/a |
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| Other Names | EVER1, Transmembrane channel-like protein 6, Tmc6, Epidermodysplasia verruciformis protein 1 |
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| Gene, Accession # | Entrez: 11322, 688280; Uniprot: Q7Z403 |
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| Catalog # | PA5-77755 |
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| Price | |
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| Order / More Info | TMC6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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