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| Antigenic Specificity | Phospho-Survivin (Thr117) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-Survivin (Thr117) Polyclonal Antibody. Survivin (IAP4) is the smallest member of the Inhibitors of Apoptosis Protein (IAP) gene family. The IAPs are involved in multiple cell functions such as cell signaling, cell division, metabolism, and exhibits differential expression in nearly all human cancers, but not in most normal tissues. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but the Survivin gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of survivin's gene expression. Survivin is ex |
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| Immunogen | n/a |
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| Other Names | API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, BIRC5, Baculoviral IAP repeat-containing protein 5, IAP4, TIAP |
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| Gene, Accession # | Entrez: 11799, 332; Uniprot: O15392, O70201 |
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| Catalog # | PA5-38334 |
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| Price | |
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| Order / More Info | Phospho-Survivin (Thr117) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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