产品详情 |
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Antigenic Specificity | Phospho-Syk (Tyr348) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, nonhuman primate, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-Syk (Tyr348) Polyclonal Antibody. Syk (spleen tyrosine kinase) is a 635 amino acid protein that contains one protein kinase domain and two SH2 domains. One of several members of the protein kinase superfamily, Syk functions as a positive effector of B cell antigen receptor (CD79)-stimulated responses, coupling CD79 with the movement of one calcium ion through one of two phospho-regulated pathways. Via its ability to influence CD79 activity and to control the movement of calicum through the cell, Syk plays an important role in a variety of cellular responses, including differentiation, phagocytosis, proliferation and B cell development. Syk expression is upregulated in T cell lymphoma, suggesting a possible role for Syk in tumorigene |
Immunogen | n/a |
Other Names | Spleen tyrosine kinase, PROTEIN-TYROSINE KINASE SYK |
Gene, Accession # | Entrez: 20963, 25155, 6850; Uniprot: P43405, P48025, Q64725 |
Catalog # | PA5-38094 |
Price | |
Order / More Info | Phospho-Syk (Tyr348) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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