产品详情 |
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Antigenic Specificity | Phospho-Syk (Tyr323, Tyr317) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-Syk (Tyr323, Tyr317) Polyclonal Antibody. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. |
Immunogen | n/a |
Other Names | EC 2.7.10.2, KSYK, SYK, Spleen tyrosine kinase, kinase Syk |
Gene, Accession # | Entrez: 20963, 6850; Uniprot: P43405, P48025 |
Catalog # | 44-233G |
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Order / More Info | Phospho-Syk (Tyr323, Tyr317) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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