| 产品详情 |
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| Antigenic Specificity | USP8 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 10 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-5 µg/mg lysate |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | USP8 Polyclonal Antibody. USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact. |
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| Immunogen | n/a |
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| Other Names | deubiquitinating enzyme 8, hUBPy, HumORF8, KIAA0055, SPG59, ubiquitin isopeptidase Y, ubiquitin specific protease 8, Ubiquitin thioesterase 8, ubiquitin thiolesterase 8, ubiquitin-specific-processing protease 8, UBPY |
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| Gene, Accession # | Entrez: 9101; Uniprot: P40818 |
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| Catalog # | A302-930A-T |
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| Price | |
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| Order / More Info | USP8 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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