产品详情 |
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Antigenic Specificity | MYZAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry: 1:200-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MYZAP Polyclonal Antibody. MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined tra |
Immunogen | n/a |
Other Names | GRINL1A, Gcom2, MYZAP-POLR2M, gcom; GRINL1A combined protein; GRINL1A combined protein Gcom12; GRINL1A complex locus protein 1; MYZAP-POLR2M protein; MYZAP-POLR2M readthrough; NMDAR1 subunit-interacting protein; glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A combined protein |
Gene, Accession # | Entrez: 100820829; Uniprot: P0CAP1 |
Catalog # | PA5-58946 |
Price | |
Order / More Info | MYZAP Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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