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| Antigenic Specificity | Phospho-GSK3 alpha/beta (Tyr279, Tyr216) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-GSK3 alpha/beta (Tyr279, Tyr216) Polyclonal Antibody. Glycogen synthase kinase-3 (GSK3) is a protein kinase that was originally identified as a regulator of glycogen synthase, a key enzyme in glycogen metabolism. Since then, it has been shown to be involved in the regulation of a diverse array of cellular functions, including protein synthesis, cell proliferation, cell differentiation, microtubule assembly/disassembly, and apoptosis. GSK3's substrate specificity is unique in that phosphorylation of substrate only occurs if a phosphoserine or phosphotyrosine is present four residues C-terminal to the site of GSK phosphorylation. There exists two isoforms of GSK3, GSK3alpha and GSK3beta, and they are strictly regulated via phosphoryla |
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| Immunogen | n/a |
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| Other Names | Phospho-Glycogen Synthase Kinase Alpha/Beta |
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| Gene, Accession # | Entrez: 2931, 2932, 56637, 606496; Uniprot: P49840, P49841, Q2NL51, Q9WV60 |
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| Catalog # | OPA1-03083 |
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| Price | |
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| Order / More Info | Phospho-GSK3 alpha/beta (Tyr279, Tyr216) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 22326953 |
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