| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Phospho-GSK3 alpha/beta (Tyr279, Tyr216) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Phospho-GSK3 alpha/beta (Tyr279, Tyr216) Polyclonal Antibody. Glycogen synthase kinase-3 alpha and beta (GSK-3 alpha, beta) are serine/threonine kinases that regulate metabolic enzymes and transcription factors, which are responsible for coordinating processes such as glycogen synthesis and cell adhesion. GSK-3 beta activity is also required for nuclear activity of Rel dimers, which mediate an anti-apoptotic response to TNF alpha in mice. GSK-3 catalytic kinase activity is controlled through differential phosphorylation of serine/threonine residues, which have an inhibitory effect, and tyrosine residues, which have an activating effect. Growth factor stimulation of mammalian cells expressing GSK-3 alpha and GSK-3 beta induces phosphorylatio |
|---|
| Immunogen | n/a |
|---|
| Other Names | Glycogen synthase kinase-3 alpha, GSK-3 alpha, Serine/threonine-protein kinase GSK3A, GSK3A |
|---|
| Gene, Accession # | Entrez: 2931, 2932, 50686, 56637, 606496, 84027; Uniprot: P18265, P18266, P49840, P49841, Q2NL51, Q9WV60 |
|---|
| Catalog # | PA5-36646 |
|---|
| Price | |
|---|
| Order / More Info | Phospho-GSK3 alpha/beta (Tyr279, Tyr216) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|