| 产品详情 |
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| Antigenic Specificity | Carbonic Anhydrase IX |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | canine, human, mouse, plant, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ChIP assay: Assay-Dependent, ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Gel Shift: Assay-Dependent, Immunocytochemistry: 1:1000, Immunofluorescence: 1:1000, Immunohistochemistry (Frozen): 1:1000, Immunohistochemistry (Paraffin): 1:1000, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Carbonic Anhydrase IX Polyclonal Antibody. Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. Because of its functionality, it has become an important diagnostic marker for various cancers, most notably renal cell carcinoma (RCC). There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increas |
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| Immunogen | n/a |
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| Other Names | CA9, CAIX, Carbonic dehydratase, Membrane antigen MN, P54 / 58N, pMW1, RCC associated protein G250, Renal cell carcinoma associated antigen G250 |
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| Gene, Accession # | Entrez: 230099, 313495, 611933, 768; Uniprot: Q16790, Q8VHB5 |
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| Catalog # | PA1-16592 |
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| Price | |
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| Order / More Info | Carbonic Anhydrase IX Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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