| 产品详情 |
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| Antigenic Specificity | Carbonic Anhydrase IX |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Carbonic Anhydrase IX Polyclonal Antibody. Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia. Therefore, CA IX has become a reliable histochemical marker of hypoxia. |
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| Immunogen | n/a |
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| Other Names | CAIX, carbonic anhydrase IX, MN, CA9 |
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| Gene, Accession # | Entrez: 230099, 768; Uniprot: Q16790, Q8VHB5 |
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| Catalog # | PA5-77885 |
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| Price | |
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| Order / More Info | Carbonic Anhydrase IX Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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