产品详情 |
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Antigenic Specificity | PHC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PHC1 Polyclonal Antibody. Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development. PHC1 (polyhomeotic homolog 1), also known as EDR1, HPH1 or RAE28, is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a ge |
Immunogen | n/a |
Other Names | Early development regulatory protein 1; hPH1; mPH1; PH1; Phc1; PHC1_HUMAN; Polyhomeotic-like protein 1; Rae28; |
Gene, Accession # | Entrez: 13619, 1911, 312690; Uniprot: P78364, Q64028 |
Catalog # | PA5-76837 |
Price | |
Order / More Info | PHC1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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