| 产品详情 |
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| Antigenic Specificity | PHC3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PHC3 Polyclonal Antibody. Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development. PHC3 (Polyhomeotic-like protein 3), also known as Early development regulatory protein 3, is a 983 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Loss of heterozygosity of the PHC3 gene was observed in human osteosarcoma tumors, suggesting that loss o |
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| Immunogen | n/a |
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| Other Names | Polyhomeotic-like protein 3; Early development regulatory protein 3; Homolog of polyhomeotic 3; hPH3; PHC3; EDR3; PH3 |
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| Gene, Accession # | Entrez: 241915, 80012; Uniprot: Q8CHP6, Q8NDX5 |
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| Catalog # | PA5-76951 |
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| Price | |
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| Order / More Info | PHC3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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