| 产品详情 |
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| Antigenic Specificity | PHD1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 8-15 µL/mg lysate, Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PHD1 Polyclonal Antibody. Prolyl hydroxylase domain proteins HIF PHD1, HIF PHD2 and HIF PHD3 (known as PHD1, PHD2 and PHD3 in rodents, respectively) can hydroxylate HIF-alpha subunits. Hypoxia-inducible factor (HIF) is a transcriptional regulator important in several aspects of oxygen homeostasis. The prolyl hydroxylases catalyze the posttranslational formation of 4-hydroxyproline in HIF-alpha proteins. HIF PHD1, which is widely expressed, with highest levels of expression in testis, functions as a cellular oxygen sensor and is important in cell growth regulation. HIF PHD1 can localize to the nucleus or the cytoplasm and is also detected in hormone responsive tissues, such as normal and cancerous mammary, ovarian and prostate epithelium. HI |
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| Immunogen | n/a |
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| Other Names | EGL nine (C.elegans) homolog 2, EGLN2, estrogen-induced tag 6, HIF prolyl hydroxylase 1, HIF-P4H 1, P4H1, prolyl hydroxylase domain-containing protein |
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| Gene, Accession # | Entrez: 112398; Uniprot: Q96KS0 |
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| Catalog # | A305-641A-M |
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| Price | |
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| Order / More Info | PHD1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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