| 产品详情 |
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| Antigenic Specificity | TTI1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TTI1 Polyclonal Antibody. Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. |
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| Immunogen | n/a |
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| Other Names | KIAA0406, smg-10, TEL2-interacting protein 1 homolog, Tel two interacting protein 1, Tel2 interacting protein 1 homolog, smg-10 homolog, nonsense mediated mRNA decay factor |
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| Gene, Accession # | Entrez: 9675; Uniprot: O43156 |
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| Catalog # | A303-451A |
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| Price | |
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| Order / More Info | TTI1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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