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Antigenic Specificity | TTK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, nonhuman primate |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunoprecipitation: 1:50, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TTK Polyclonal Antibody. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. |
Immunogen | n/a |
Other Names | OTTHUMP00000016778; OTTHUMP00000220743; cancer/testis antigen 96; dual specificity protein kinase TTK; monopolar spindle 1-like 1; phosphotyrosine picked threonine kinase; phosphotyrosine picked threonine-protein kinase |
Gene, Accession # | Entrez: 7272; Uniprot: P33981 |
Catalog # | PA5-17286 |
Price | |
Order / More Info | TTK Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |