产品详情 |
Edit |   |
Antigenic Specificity | PLXDC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 0.5-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PLXDC2 Polyclonal Antibody. Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors. |
Immunogen | n/a |
Other Names | UNQ2514/PRO6003, TEM7R; 1200007L24Rik; plexin domain-containing protein 2; tumor endothelial marker 7-related protein |
Gene, Accession # | Entrez: 361282, 67448, 84898; Uniprot: Q6UX71, Q9DC11 |
Catalog # | PA5-20466 |
Price | |
Order / More Info | PLXDC2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|