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| Antigenic Specificity | PLXNA3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Western Blot: 1:100 - 1:250 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PLXNA3 Polyclonal Antibody. Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. |
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| Immunogen | n/a |
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| Other Names | Plxn3; PLXN4; PLXNA3; SEX; XAP-6; HSSEXGENE; plexin A3; plexin-4; Plexin-4; plexin-A3; Plxn3; PLXN3; PLXN4; Semaphorin receptor SEX; Sex chromosome X transmembrane protein of HGF receptor family 3; SEXPLEXIN-A3; 6.3; XAP-6 |
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| Gene, Accession # | Entrez: 55558; Uniprot: P51805 |
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| Catalog # | PA5-66227 |
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| Price | |
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| Order / More Info | PLXNA3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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