产品详情 |
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Antigenic Specificity | Filensin |
Clone | OTI3H6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Filensin Monoclonal Antibody (OTI3H6). More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | n/a |
Other Names | CP115, CP94, LIFL-H, cytoskeletal protein, 115 KD, filensin, lens fiber cell beaded-filament structural protein CP 115, lens intermediate filament-like heavy |
Gene, Accession # | Entrez: 631; Uniprot: Q12934 |
Catalog # | MA5-26646 |
Price | |
Order / More Info | Filensin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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