| 产品详情 |
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| Product Name | Recombinant Mouse Serine/threonine-protein kinase VRK1 (Vrk1) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 53.7kDa. Full Length: 1-140aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Mus musculus (Mouse). Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Serine/threonine-protein kinase 51PK; Vaccinia-related kinase 1 |
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| Gene, Accession, CAS # | Vrk1, UniProt: Q80X41 |
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| Catalog # | RPC25439 |
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| Order / More Info | Recombinant Mouse Serine/threonine-protein kinase VRK1 (Vrk1) from BIOMATIK |
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| Product Specific References | n/a |
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