产品详情 |
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Antigenic Specificity | PRELP |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Immunocytochemistry: 5-15 µg/mL, Immunofluorescence: 5-15 µg/mL, Neutralization: 0.2-1.2 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PRELP Polyclonal Antibody. PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. |
Immunogen | n/a |
Other Names | MST161, MSTP161, SLRR2A, 55 kDa leucine-rich repeat protein of articular cartilage, prolargin, prolargin proteoglycan, proline-arginine-rich end leucine-rich repeat protein |
Gene, Accession # | Entrez: 5549; Uniprot: P51888 |
Catalog # | PA5-47841 |
Price | |
Order / More Info | PRELP Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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