| 产品详情 |
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| Product Name | Bezafibrate |
| Description | Purity >98%. Bezafibrate is a well established pan-peroxisome proliferator-activated receptor (pan-PPAR) activator. This fibrate drug has over 25 years of therapeutic use with a good safety profile. The fibrate class of drugs are generally known as PPARAlpha agonists, but bezafibrate appears to activate PPARDelta and PPARGamma as well. Bezafibrate activates human PPARAlpha, PPARDelta, and PPARGamma with EC50 values of 50, 20, and 60 µM, respectively, in a cell-based transcription assay. Bezafibrate is used to treat hyperlipidemia. It helps lower low-density lipoprotein cholesterol and triglycerides while raising high-density lipoprotein cholesterol levels. It also improves insulin sensitivity and reduces blood glucose levels, which in combination with the cholesterol effects significantly lowers the incidence of cardiovascular events and development of diabetes in patients with features of metabolic syndrome. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic acid, Benzofibrate, Bezalip, Bezatrol, BM 15075, Difaterol |
| Gene, Accession, CAS # | CAS: 41859-67-0 |
| Catalog # | LS-H6781 |
| Price | |
| Order / More Info | Bezafibrate from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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