| 产品详情 |
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| Antigenic Specificity | WIPI2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | WIPI2 Polyclonal Antibody. WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes. |
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| Immunogen | n/a |
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| Other Names | ATG18B, Atg21, WIPI-2, WD repeat domain phosphoinositide-interacting protein 2, WD40 repeat protein interacting with phosphoinositides 2, WIPI49-like protein 2 |
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| Gene, Accession # | Entrez: 26100, 74781; Uniprot: Q80W47, Q9Y4P8 |
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| Catalog # | A305-324A |
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| Price | |
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| Order / More Info | WIPI2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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