产品详情 |
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Antigenic Specificity | WIPI2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200, Western Blot: 0.4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | WIPI2 Polyclonal Antibody. WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes. |
Immunogen | n/a |
Other Names | WIPI2, WD repeat domain phosphoinositide interacting 2, WIPI-2, WD40 repeat protein interacting with phosphoinositides 2, WIPI49-like protein 2, ATG18B, ATG21, CGI-50 |
Gene, Accession # | Entrez: 26100, 288498, 74781; Uniprot: Q6AY57, Q80W47, Q9Y4P8 |
Catalog # | PA5-54098 |
Price | |
Order / More Info | WIPI2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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