产品详情 |
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Antigenic Specificity | IRF4 |
Clone | 16 HCLC |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IRF4 Antibody (16 HCLC), ABfinity™ Rabbit Oligoclonal. The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found. |
Immunogen | n/a |
Other Names | Interferon regulatory factor 4 |
Gene, Accession # | Entrez: 3662; Uniprot: Q15306 |
Catalog # | 711295 |
Price | |
Order / More Info | IRF4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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