| 产品详情 |
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| Antigenic Specificity | IRF4 |
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| Clone | 3E4 |
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| Host Species | Rat |
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| Reactive Species | human, mouse |
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| Isotype | IgG1, kappa |
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| Format | eFluor 660 conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IRF4 Monoclonal Antibody (3E4), eFluor 660, eBioscience™. The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found. |
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| Immunogen | n/a |
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| Other Names | LSIRF, MUM1 |
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| Gene, Accession # | Entrez: 16364, 3662; Uniprot: Q15306, Q64287 |
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| Catalog # | 50-9858-82 |
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| Price | |
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| Order / More Info | IRF4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25416805, 25681333, 26801566, 26851186, 27376549, 27897162 |
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