| 产品详情 |
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| Antigenic Specificity | CUBN |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:40, Western Blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CUBN Polyclonal Antibody. Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in t |
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| Immunogen | n/a |
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| Other Names | CUBN, Cubulin, gp280, IFCR, MGA1, cubilin, cubilin (intrinsic factor-cobalamin receptor), gp280, IFCR, MGA1 |
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| Gene, Accession # | Entrez: 8029; Uniprot: O60494 |
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| Catalog # | PA5-67616 |
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| Price | |
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| Order / More Info | CUBN Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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