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| Antigenic Specificity | CUEDC2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CUEDC2 Polyclonal Antibody. The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to |
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| Immunogen | n/a |
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| Other Names | HOYS6; C10orf66; bA18I14.5; CUE domain-containing protein 2 |
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| Gene, Accession # | Entrez: 79004; Uniprot: Q9H467 |
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| Catalog # | PA5-65315 |
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| Price | |
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| Order / More Info | CUEDC2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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