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Antigenic Specificity | CUGBP1 |
Clone | 3B1 |
Host Species | Mouse |
Reactive Species | bovine, human, mouse, nonhuman primate, porcine, rabbit, rat |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1 µg/1x10^6 cells, Gel Shift: Assay-Dependent, Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Frozen): 1:100-1:500, Immunohistochemistry (Paraffin): 1:100-1:500, Immunoprecipitation: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CUGBP1 Monoclonal Antibody (3B1). Myotonic dystrophy (MD) is an autosomal dominant neuromuscular disease that is associated with a (CTG)n repeat expansion in the 3'-untranslated region of the myotonin protein kinase (Mt-PK) gene. A (CUG) n oligonucleotides triplet repeat pre-mRNA/mRNA binding protein may play an important role in DM pathogenesis. HeLa cell protein, CUG-BP1, has been purified based upon its ability to bind specifically to (CUG) 8 oligonucleotides in vitro. CUG-BP1 is the major (CUG) 8 binding activity in normal cells. CUG-BP1 has been identified as isoforms of a novel heterogeneous nuclear ribonucleoprotein (hnRNP), hNab50. The CUG-BP/hNab50 protein is localized predominantly in the nucleus and is associated with polyadenyla |
Immunogen | n/a |
Other Names | RP23-147D3.7, 1600010O03Rik, AA407467, Brunol2, CUG-BP, CUG-BP1, CUGBP, D2Wsu101e, HNAB50, NAB50 |
Gene, Accession # | Entrez: 100354668, 100514512, 10658, 13046, 362160, 540475; Uniprot: P28659, Q4QQT3, Q92879 |
Catalog # | MA1-16675 |
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Order / More Info | CUGBP1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20685272 |
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