产品详情 |
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Antigenic Specificity | CD40 |
Clone | 5C3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | allophycocyanin (APC) conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.06 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD40 Monoclonal Antibody (5C3), APC, eBioscience™. The CD40 antigen is a single chain glycoprotein that is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin's disease associated antigen, CD30. CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of CD40, which may be importan |
Immunogen | n/a |
Other Names | Bp50, CDW40, MGC9013, TNFRSF5, p50 |
Gene, Accession # | Entrez: 958; Uniprot: P25942 |
Catalog # | 17-0409-42 |
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Order / More Info | CD40 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 23027536, 23825947, 24123687, 25949876, 26956612, 27099316, 27974697 |
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