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Antigenic Specificity | CD40 |
Clone | HM40-3 |
Host Species | Armenian Hamster |
Reactive Species | mouse, rat |
Isotype | IgM, kappa |
Format | unconjugated, functional grade |
Size | 1 mg |
Concentration | n/a |
Applications | Flow Cytometry: 1 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD40 Monoclonal Antibody (HM40-3), Functional Grade, eBioscience™. The CD40 antigen is a single chain glycoprotein that is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin's disease associated antigen, CD30. CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of CD40, which |
Immunogen | n/a |
Other Names | Bp50, CDW40, MGC9013, TNFRSF5, p50 |
Gene, Accession # | Entrez: 171369, 21939; Uniprot: P27512 |
Catalog # | 16-0402-86 |
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Order / More Info | CD40 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 17923094, 19190348, 21709240, 21971520, 22392994, 22590614, 23382073, 23496831, 23921550, 24391649, 24726358, 25483076, 26787905, 28003812, 28078005, 28819104, 29127283 |
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