产品详情 |
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Antigenic Specificity | GluR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GluR1 Polyclonal Antibody. GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
Immunogen | n/a |
Other Names | GPRC1A, GRM1A, MGLUR1, MGLUR1A, mGlu1, metabotropic glutamate receptor 1 |
Gene, Accession # | Entrez: 2890; Uniprot: P42261 |
Catalog # | PA5-32425 |
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Order / More Info | GluR1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20506566, 21182898, 21276808, 21490215, 21692887, 22470150, 23325250, 23502536, 23825406, 24035918, 27225765, 27383008 |
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