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Antigenic Specificity | GluR2 |
Clone | 6C4 |
Host Species | Mouse |
Reactive Species | human, mouse, nonhuman primate, rat |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 0.5-5 µg/mL, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:100, Western Blot: 2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GluR2 Monoclonal Antibody (6C4). Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isof |
Immunogen | n/a |
Other Names | AMPA-selective glutamate receptor 2, GluR-2, GluR-B, GluR-K2, GLUR2, GLURB, Glutamate receptor 2, Glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA 2, GRIA2, HBGR2 |
Gene, Accession # | Entrez: 14800, 2891, 29627; Uniprot: P19491, P23819, P42262 |
Catalog # | 32-0300 |
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Order / More Info | GluR2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 12761821, 14741100, 1710829, 17472959, 18094256, 18096191, 18755203, 23373691, 24667777, 24784359, 25403753, 26482898, 26539912, 27117477, 9784283 |
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