| 产品详情 |
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| Antigenic Specificity | TDP-43 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | chicken, human, mouse, nonhuman primate, Xenopus laevis, zebrafish |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry: Assay-Dependent, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TDP-43 Polyclonal Antibody. The HIV1 virus gives rise to acquired immunodeficiency syndrome (AIDS). HIV1 contains an RNA genome which produces chromosomally integrated DNA during cellular replication. Gene activation of HIV1 by the transactivator Tat requires an RNA regulatory element TAR which is located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to the chromosomally integrated TAR DNA, preventing HIV1 expression. Additionally, this protein regulates alternative splicing of the CTFR gene, a similar pseudogene on chromosoome 20. TARDBP has also been recently been shown to abnormally accumulate in the post-mortem brain tissue of individuals diagnosed with ALS (Amyotrophic Lateral Scleros |
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| Immunogen | n/a |
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| Other Names | TARD binding protein , TAR DNA-binding protein 43 , TDP-43 , TDP43 |
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| Gene, Accession # | Entrez: 230908, 23435, 325052, 380329, 419453; Uniprot: Q13148, Q5ZLN5, Q921F2 |
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| Catalog # | PA1-16996 |
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| Price | |
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| Order / More Info | TDP-43 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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