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| Product Name | Recombinant Human C-C motif chemokine 1 protein (CCL1) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 18.4kDa. Full Length of Mature Protein: 26-177aa. C-terminal 6xHis-tagged. Homo sapiens (Human). Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Interleukin-7; IL-7; IL7 |
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| Gene, Accession, CAS # | IL7, UniProt: P13232 |
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| Catalog # | RPC26895 |
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| Order / More Info | Recombinant Human C-C motif chemokine 1 protein (CCL1) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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