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| Product Name | Recombinant Human C-C motif chemokine 17 protein (CCL17) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 14.2kDa. Full Length of Mature Protein: 20-134aa. C-terminal 6xHis-tagged. Homo sapiens (Human). IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Interleukin-5; IL-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRF; IL5 |
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| Gene, Accession, CAS # | IL5, UniProt: P05113 |
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| Catalog # | RPC26875 |
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| Order / More Info | Recombinant Human C-C motif chemokine 17 protein (CCL17) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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